Chemists are first to synthesize ocean-based molecule that could fight Parkinson’s In producing lissodendoric acid A, the team used a method they say may help accelerate the process of drug discovery 23-Jan-2023 - Organic chemists at UCLA have created the first synthetic version of a molecule recently discovered in a sea sponge that may have therapeutic benefits for Parkinson’s disease and similar disorders. The molecule, known as lissodendoric acid A, appears to counteract other molecules that can damage ... Active ingredient research drug discovery drug research +3 Loading...
Study identifies new dementia risk genes through novel testing approach Mass screening of genetic variants in a single experiment 25-Aug-2022 - A new UCLA-led study has identified multiple new risk genes for Alzheimer’s disease and a rare, related brain disorder called progressive supranuclear palsy (PSP) by using a combination of new testing methods allowing for mass screening of genetic variants in a single experiment.The study, ... Alzheimer's disease brain disorders genes +2 Loading...
Researchers develop molecular traps to target SARS-CoV-2 Joint effort by UC Riverside and UCLA scientists aims to stop the COVID-19-spreading virus from attacking immune cells 02-Feb-2022 - A research team led by scientists at UC Riverside and UCLA has engineered novel nanoparticles to serve as “molecular traps” to target SARS-CoV-2, the virus that spreads COVID-19. The traps bind to SARS-CoV-2 and prevent it from attacking macrophages — white blood cell that surround and kill ... coronaviruses Covid-19 immune cells +4 Loading...
A longer-lasting COVID vaccine? Study points the way 17-Dec-2021 - Researchers at theEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLAhave identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses.The findings suggest that a component of this ... coronaviruses Covid-19 SARS-CoV-2 +2 Loading...
Breakthrough in the production of three-dimensional molecular structures New dimensions in organic chemistry through light-mediated synthesis 07-Apr-2021 - A major goal of organic and medicinal chemistry in recent decades has been the rapid synthesis of three-dimensional molecules for the development of new drugs. These drug candidates exhibit a variety of improved properties compared to predominantly flat molecular structures, which are reflected ... Cycloaddition drug candidates medicinal chemistry +3 Loading...
Why we need sleep In very early life, sleep helps build the brain's infrastructure, but it then takes on an entirely new decluttering role 22-Sep-2020 - Prolonged sleep deprivation can lead to severe health problems in humans and other animals. But why is sleep so vital to our health? A UCLA-led team of scientists has answered this question and shown for the first time that a dramatic change in the purpose of sleep occurs at the age of about ... brain sleep sleep research Loading...
Stingray soft robot could lead to bio-inspired robotics 16-Jan-2018 - UCLA bioengineering professor Ali Khademhosseini has led the development of a tissue-based soft robot that mimics the biomechanics of a stingray. The new technology could lead to advances in bio-inspired robotics, regenerative medicine and medical diagnostics.The simple body design of stingrays, ... electrodes engineering medical diagnostics +3 Loading...
Fat cells may inactivate chemotherapeutic drug 09-Nov-2017 - Adipocytes, or fat cells, can absorb and metabolize the chemotherapeutic agent daunorubicin, reducing the effectiveness of the drug and potentially contributing to poorer treatment outcomes."Anthracyclines such as daunorubicin are important chemotherapy agents used in a variety of cancers in ... adipocytes anthracyclines cancer +6 Loading...
How to amplify or stifle signals for immune responses 09-Mar-2017 - T cells, the managers of our immune systems, spend their days shaking hands with another type of cell that presents small pieces of protein from pathogens or cancerous cells to the T cell. But each T cell is programmed to recognize just a few protein pieces, known as antigens, meaning years can ... antigens cells drugs +12 Loading...
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Chemists are first to synthesize ocean-based molecule that could fight Parkinson’s In producing lissodendoric acid A, the team used a method they say may help accelerate the process of drug discovery View news
Study identifies new dementia risk genes through novel testing approach Mass screening of genetic variants in a single experiment View news
Researchers develop molecular traps to target SARS-CoV-2 Joint effort by UC Riverside and UCLA scientists aims to stop the COVID-19-spreading virus from attacking immune cells View news
A longer-lasting COVID vaccine? Study points the way View news
Breakthrough in the production of three-dimensional molecular structures New dimensions in organic chemistry through light-mediated synthesis View news
Why we need sleep In very early life, sleep helps build the brain's infrastructure, but it then takes on an entirely new decluttering role View news
Model estimates lifetime risk of Alzheimer's dementia using biomarkers View news
Stingray soft robot could lead to bio-inspired robotics View news
Fat cells may inactivate chemotherapeutic drug View news
How to amplify or stifle signals for immune responses View news
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Chemists are first to synthesize ocean-based molecule that could fight Parkinson’s In producing lissodendoric acid A, the team used a method they say may help accelerate the process of drug discovery view news
Study identifies new dementia risk genes through novel testing approach Mass screening of genetic variants in a single experiment view news
Researchers develop molecular traps to target SARS-CoV-2 Joint effort by UC Riverside and UCLA scientists aims to stop the COVID-19-spreading virus from attacking immune cells view news
Why we need sleep In very early life, sleep helps build the brain's infrastructure, but it then takes on an entirely new decluttering role view news
Model estimates lifetime risk of Alzheimer's dementia using biomarkers view news
Stingray soft robot could lead to bio-inspired robotics view news
Fat cells may inactivate chemotherapeutic drug view news
How to amplify or stifle signals for immune responses view news
Combatting antimicrobial resistance with smartphones A simple and inexpensive attachment could help to expand testing to regions with limited resources. view news
Research finds possible answer to why some develop Alzheimer’s - and others don’t view news
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